The presentation detailed the development strategy and outstanding skin improvement effects of this cutting-edge skincare delivery technology. The ‘Encapguard’ system consists of two core products, ‘Encapguard Cera-S’ and ‘Encapguard Cera-LNP5’, utilizing an advanced substance delivery mechanism.
These products penetrate the stratum corneum, where the ceramide capsules naturally break down to strengthen and repair the skin barrier. Notably, the active ingredients are uniformly delivered to the basal layer of the epidermis, maximizing their skin-enhancing efficacy and setting a new standard for skincare innovation.
Distinctive Delivery Mechanism with Proven Stability and Transdermal Efficacy ‘Encapguard’ is designed using liposome and lipid nanoparticle (LNP) technologies, with its structural stability confirmed through Cryo-TEM analysis. A 3-month long-term stability test showed no changes in particle size or physicochemical properties.
In transdermal permeation tests, the system demonstrated a 200% improvement in penetration efficiency compared to conventional methods. The 3D imaging results visually confirmed the uniform distribution of active ingredients within the skin.
- Encapguard Cera-S: Provides sustained effects by delivering small amounts of active ingredients over an extended period.
- Encapguard Cera-LNP5: Rapidly delivers large quantities of active ingredients for quick efficacy.
Skin Protection Effects and Clinical Verification
The protective effects of the delivery system were evaluated through MTT assays and anti-inflammatory tests. In 3D artificial skin models, the products significantly enhanced skincell viability and reduced inflammation markers, demonstrating their capacity to protect the
skin from external stressors.
Further validation was conducted through TEWL (transepidermal water loss) and moisturization tests in clinical trials. The results showed that both delivery systems effectively reduced TEWL and improved hydration, substantiating their ability to strengthen and restore the skin barrier.
Future Development and Collaborative Expansion
KCI is actively pursuing collaborations with domestic and international cosmetics companies to integrate ‘Encapguard’ technology into new product lines. In addition, three new formulations—Encapguard Cera-Cubosome, Encapguard Cera-Emulsion, and Encapguard Cera-Powder—featuring high concentrations of ceramides, are set to launch in the first quarter of next year. KCI is also accelerating the development of raw materials combining technology with antioxidants, vitamins, peptides, and other active ingredients. A KCI representative stated, “This research demonstrates the groundbreaking potential of our delivery technology. We are committed to advancing sustainable innovations that will solidify our competitiveness in the global market.”
KCI is poised to continue leading skincare innovation through ongoing research and strategic collaborations, paving the way for the next generation of skincare solutions.
