An innovative and biomimetic way to reduce lower face sagging

Published: 20-Nov-2023

As we age, the face naturally loses collagen. The structure of the skin progressively changes, with a characteristic sagging and a loss of elasticity. Seppic has developed SAGACIOUS, a biomimetic anti-sagging ingredient to reduce the appearance of drooping skin by improving skin firmness down the deepest layers of the skin

Sagging skin, a rising concern

Sagging skin is one of the most concerning esthetic issues for the aging population. As facial aging occurs, the skin around the cheeks, mouth, and nasolabial folds may exhibit this characteristic droopiness. In fact, 67% of women are most concerned about this feature of facial aging, which can negatively affect the appearance of the face and accentuate signs of fatigue and stress(1) .

As the skin gradually loses its elasticity and biomechanical properties, it loses its ability to resist gravitational force, resulting in the appearance of even looser skin on the lower part of the face and pronounced nasogenian folds. At the level of the skin, the dermo-epidermal junction becomes thinner, the mechanical properties in the dermis are reduced and there is less interaction between cells at the dermo-hypodermal junction.

An innovative active ingredient to improve skin firmness

SAGACIOUS™ (INCI: Propanediol (and) Himanthalia Elongata Extract) is a biomimetic anti-sagging ingredient from Himanthalia elongata seaweed that provides a global and effective anti-aging strategy.

Indeed, the innovation lies in its action that targets all the layers of the skin, from the dermo-epidermal junction to the dermis and deep into the dermo-hypodermal junction. This complete action makes it possible to reduce lower facial sagging and improve skin firmness.

Tested in vivo for 28 days, SAGACIOUS™ significantly improves skin firmness by 8 times compared to placebo. Its effect was also tested on reducing the visibility of nasogenian folds, showing a 7.1% reduction in visibility compared to placebo.


(1) Survey conducted in 2015 by the American Society for Dermatologic Surgery, 7315 responses, whatever the age.

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