Acetyl Zingerone (AZ) is a multi-targeted antiaging molecule designed to counteract aging before it happens and to reverse the signs of photoaged skin. AZ neutralizes photooxidative stress and nurtures skin’s own ability to maintain the integrity of the ECM for optimal health and appearance throughout life. AZ’s key attributes include: (1) All-in-one –Antioxidant, Physical Quencher & Selective Chelator – First-in-the Industry; (2) Ability to reduces both immediate & delayed DNA damage (↓CPDs) - First-in-the Industry; (3) Photochemical stability that provides ongoing performance as an antioxidant on sun-exposed skin in contrast to many conventional antioxidants, such as vitamin E and resveratrol; (4) Validated performance in placebo-controlled clinical studies, which revealed significant improvements in skin’s defenses & reductions in wrinkle, pigmentation and skin redness in photoaged skin without using sunscreens; (5) Gentleness that balances skin microbiome diversity and stimulates skin friendly Staph. epidermidis by >20%. REACH registered. Patented product.
There is a shortage of well-validated treatments to prevent the tell-tale features of skin aging (fine lines, wrinkles, sagging, uneven skin tone, age spots), which leaves consumers settling for less effective cosmetic solutions. Skin aging also impairs wound healing, which can compromise skin’s own ability to recover from surgery, cutaneous infections, or chronic ulcers. Synoxyl® AZ is a novel topical agent, whose molecular structure was inspired by that of Zingerone from the Ginger plant found in nature. At Sytheon we have conducted extensive studies that document AZ’s clinical benefits and that shed light on the multiple mechanisms by which AZ works. Synoxyl® AZ provides a translational step forward towards development of more efficacious molecules to treat or prevent the consequences of intrinsic and extrinsic skin aging.