Epigenetic well-aging, a new pathway for skin longevity

Published: 5-Jun-2026 Featured companies: Naolys
Skin Care Wellness

Aethelis Granata, Naolys’ plant exosome biotech active, introduces a new SUMOylation-driven approach to well-aging

This breakthrough innovation has been recognised by both the C&T Allē Awards and the BSB Awards, earning 1st place in their respective anti-aging and skin rejuvenation categories.

From correction to adaptation

Aethelis Granata is the first cosmetic active born from Naolys’ proprietary ExoCell® plant exosome technology, combining plant intelligence, epigenetic science, and a novel well-aging approach.

Feedback from the C&T experts jury:

A novel pathway to anti-aging, with data showing the difference between traditional plant extracts and plant exosomes

Rather than focusing solely on correcting visible signs of aging, Aethelis Granata targets SUMOylation, an adaptive cellular mechanism involved in chromatin organisation, DNA repair and cellular resilience.

By leveraging plant exosomes as biological messengers, Aethelis Granata supports cellular adaptation mechanisms associated with skin longevity, resilience and healthy aging.

Adaptive longevity in action

Epigenetic well-aging, a new pathway for skin longevity

Clinical results demonstrated that targeting adaptive epigenetic pathways can translate into visible wrinkle reduction.

Beyond instrumental measurements, participants also reported visibly healthier-looking skin, and highlighted the perceptible rejuvenating effect.

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