CAPILIA LONGA PPF is able to produce an epigenetic reset of the hair bulb, reactivating the activity of these latent dermal papilla cells and promoting the hair follicle regeneration to create new hair.
Hair growth Re-Activation by genuine Plant Growth Factors
Hair loss is a problem that affects both men and women and has diverse origins, but despite the different etiologies, there is a common link between them: dermal papilla cells become latent, and all the hair growth processes stop. The multiactive ingredient CAPILIA LONGA PPF made from Curcuma longa (Turmeric) callus culture offers a solution to the problem. Seeing how hair loss starts when Dermal Papilla Cells become inactive, the solution of the problem goes through their reactivation. CAPILIA LONGA PPF is able to produce an epigenetic reset of the hair bulb, reactivating the activity of these latent dermal papilla cells and promoting the hair follicle regeneration to create new hair.
Curcuma longa is a tropical and subtropical plant characterized by the existence of very ramified, cylindrical and orange rhizome. These rhizomes are a modified root that acts as a storage and resistance organ. They grow endlessly and have excellent regenerative properties.
Rich in curcuminoids (mainly curcumin), Curcuma longa is the most studied plant in biomedicine, having a huge potential, with more than 400 pre-clinic assays described in the literature and more than 1000 publications, showing its multiple properties (antioxidant, anti-inflammatory, wound healing, antimicrobial, DNA protection, etc...)
CAPILIA LONGA PPF represents a new activity profile for Curcuma longa, claiming the Phyto-Peptidic Fractions as a new range of bioactives from the species (Curcumin is only the 2-5% of turmeric powder). The ingredient is the concentrated secretome of totipotent cells from the rhizome (root) of Turmeric. This secretome is rich in signaling peptides specially designed to create the optimal micro-environment to re-activate hair growth, achieving an epigenetic reset of hair bulb and hair follicle regeneration.
CAPILIA LONGA PPF acts as a Hair 3D Bio-Printer, resetting and guiding the hair follicle growth with a bio-software (Phyto-Peptidic Frations), nourishing at the same time the hair follicle growth with an innovative Bio-Ink (Exclusive Nutritive Blend)
A GREAT TECHNOLOGY BEHIND
As expert developer of plant totipotent cell cultures, Vytrus Biotech launches a new range of products arising from the proprietary Plant Cell Biofactories Technology Platform, introducing the Phyto-Peptidic Fractions (PPF). They represent the first generation of genuine plant peptides, a revolutionary discovery that opens the door to a new generation of cosmetics.
Vytrus Biotech, through a driven Growth Factor Control development process has been able to identify, produce and concentrate these Phyto-Peptidic Fractions from an optimized culture of totipotent cells.
These PPF are the ultimate responsible of the extremely high regenerative properties of totipotent cells and, for the first time, this astonishing potential can be used in cosmetics
That makes of Phyto-Peptidic Fractions the first cosmetic active of this category able to maintain the skin regenerative potential.
(To measure ability of ingredient to activate proliferation and release of key growth factors)
The results show up to 177% of Proliferation Index (compared to Not Treated cells), showing a Higher effect that other Growth Factors (HGF, FGF, VEGF, IGF-1) and even higher than Minoxidil (169%).
Up to 115% of Production Index (compared to Not Treated cells) from the HFDPC, showing a faster activity than Minoxidil (36%).
Up to 6,3 times miRNA-31 Expression Stimulation (compared to Control)
Up to 40% miRNA-22 Expression Index Reduction (compared to Control)
Panel of 40 volunteers
* Male and Female androgenetic alopecia, seasonal alopecia, diffuse alopecia, Hair loss due to technical processes, fragility, menopause.
Measurement of:
The results show:
Up to 89 % hair loss reduction after 150 days (average: 57 %)
Up to 52 % hair density increase after 150 days (average: 17 %, i.e. 13500 new hairs)
27 % increase of A/T ratio after 150 days
Improvement of hair anchoring and general hair strengthening.
Formulation: Water and ethanol soluble. Incorporation during the cooling phase (<40ºC
Dossage: Suggested use level: 0,5 -2%
Declarations: Free of GMO, BSE, listed CMR, VOC, heavy materials, listed allergens, parabens, phenoxyethanol, aflatoxins, pesticides and contaminant.
INCI: Curcuma Longa (Turmeric) Callus Conditioned Media
| In vivo: | In vitro: |
|---|---|
| Skin Tolerance (patch test) | Skin irritation potential |
| Sensibilisation (HRIPT) | Ocular irritant potential |
| Mutaqenicity | |
| Citotoxicity |
