It is the first cosmetic ingredient able to act both in the pre- and post-synaptic pathways of muscle contraction and in a new SNARE protein (Munc-18). Munc-18 binds to syntaxin allowing the assembly of the SNARE complex. Pre-synaptic: Munapsys™ competes with Munc-18 for its position in syntaxin, obstructing SNARE complex assembly and the release of the acetylcholine (ACh) neurotransmitter into the synapse. Post-synaptic: ACh activates clustered AChR, inducing a depolarization and opening Ca2+ channels allowing actomyosin cross-bridge and sliding for muscle contraction. Munapsys™ modulates AChR clustering, depolarization, Ca2+ mobilization, and actomyosin cross-bridge and sliding.
Munapsys™ mechanism is a real upgrade in the expression lines field, with proven efficacy compared with a benchmark combination even at a lower dose. Let yourself enjoy from a new generation of botulinum-like ingredients. A safe, real beauty filter.
To learn more about Munapsys™ visit www.lipotrue.com or contact us at info@lipotrue.com
