Exosomes, also known as Ectosomes or Small Extracellular Vesicles (sEVs), are naturally secreted by cells and surrounded by a lipid membrane. These vesicles contain crucial biological components such as DNA, RNA, proteins, and various bioactive compounds.
Contrary to the growing interest in synthetic or biomimetic exosomes, which are engineered to mimic natural exosome functions but differ structurally, Vytrus Biotech focuses on natural plant exosomes structurally intact. Their similarity to mammalian exosomes allows them to effectively penetrate human cells, facilitating Cross-kingdom communication, while also enabling their customization to meet specific cosmetic needs.
Vytrus Biotech envisions exosomes as "natural biological communicators”, essential in transmitting vital biological information. In cosmetics, a significant advantage of plant exosomes is their superior transdermal delivery capabilities. These exosomes penetrate the stratum corneum through appendageal, intercellular, and transcellular pathways, ensuring efficient absorption and rapid improvement in skin parameters. Their lipid membrane structure is key to this process, facilitating endocytosis through mechanisms like clathrin, RAFTs, caveolae, pinocytosis, phagocytosis, direct fusion, and receptor mediation. This highly fusogenic nature allows them to deliver bioactive compounds deep into the skin layers, ensuring maximum efficacy.
Furthermore, Vytrus’s research highlights the competitive advantages of natural plant exosomes over synthetic and animal-derived exosomes. Unlike their synthetic counterparts, plant exosomes are structurally intact and biomimetic, offering a natural, low-immunogenic, and non-toxic alternative. They are also more stable and environmentally resilient, making them ideal for cosmetic applications. Compared to animal-derived exosomes, plant exosomes are vegan-friendly and free from ethical concerns, positioning them as a superior choice for the modern, conscious consumer.
Vytrus's plant exosomes are produced through advanced biotechnology, achieving high concentrations of billions of exosomes per milliliter, surpassing traditional plant sources. This high concentration enables effective delivery of molecular information to human cells, enhancing anti-inflammatory effects, hydration, regeneration, and skin homeostasis.
In its aim of advancing the latest cosmetic science, Vytrus' research has led to the discovery of Exosomic Peptides™ within these plant exosomes, introducing a new cosmetic ingredient that offers significant anti-aging, anti-inflammatory, and anti-wrinkle benefits.
Through its biotechnology platforms, Vytrus has effectively produced and characterized real plant exosomes from Curcuma longa and Centella asiatica plant stem cell cultures, obtaining a high exosome concentration vs traditional plant sources reaching levels of billions of exosomes/ml. Curcuma longa exosomes have very interesting applications in the improvement of skin hydration and regeneration, as well as the hair density increase and delay of hair loss. Whereas Centella asiatica has the potential to encapsulate and protect compounds of interest such as growth factors, proteins, and peptides.
Stay ahead in the cosmetic industry with the latest advancements in plant biotechnology. Visit Vytrus Biotech news to learn how plant exosomes and Exosomic Peptides™ can transform your product formulations.
