RJMPDRN REC: The World’s First Recombinant Salmon PDRN for Anti-Aging and Regeneration

Published: 15-Oct-2025

Uniproma proudly introduces RJMPDRN REC, shortlisted for the 2025 Best Ingredient Award at in-cosmetics Latin America. As the world’s first recombinant salmon PDRN, it represents a major advancement in nucleic acid biotechnology

Developed via a patented biological synthesis platform, it leverages engineered bacteria to precisely replicate target PDRN sequences, offering a complete alternative to traditional salmon-derived extraction.

This ensures 100% sequence accuracy, consistent molecular weight, structural homogeneity, and zero animal-derived components, while enabling fully traceable, sustainable, and scalable production to meet global regulatory and market requirements.

Extensive in vitro studies demonstrate potent cell-level benefits across repair, regeneration, anti-aging, and anti-inflammatory functions.

  • Fibroblast migration is enhanced to 131% of control, indicating strong wound-healing and skin repair potential.
  • Increases type I collagen by 1.5× and type III collagen by 1.1×, outperforming conventional salmon PDRN, which translates into noticeable improvements in skin firmness, elasticity, and wrinkle reduction.
  • Effectively inhibits pro-inflammatory mediators, IL-6 and TNF-α, confirming its anti- inflammatory efficacy.
  • Achieves up to 93% cell migration when combined with hyaluronic acid within 24 hours, highlighting exceptional synergistic potential for combination formulations.

The controlled fragment length, uniform structure, and optimized sequence of RJMPDRN® REC also contribute to superior transdermal performance and reproducibility, overcoming batch-to-batch variability inherent in traditional extraction methods.

RJMPDRN® REC defines a new standard for DNA-based skin care actives, providing brands with a scientifically validated solution for precision repair, anti-aging, and inflammation control. Its production is fully environmentally responsible, eliminating the need for animal- derived materials and reducing pressure on marine ecosystems, offering a truly sustainable solution that meets the growing demand for ethical and eco-conscious skin care ingredients.

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