The Research Institute for Fragrance Materials (RIFM) has published a safety assessment in the journal Food and Chemical Toxicology stating that the ingredient methyl 2-octynoate is safe for use in cosmetics at prescribed dosages.
Methyl 2-octynoate, which is also known as methyl heptine carbonate, MHC 2-octynoic acid methyl ester and Folione (a Givaudan trademark), has been cited as a moderately frequent cause of
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