Push back the limits of cell aging

Published: 20-Feb-2025

SILAB presents new efficacy studies on LONGEVICELL, a natural anti-aging active ingredient obtained from myrtle leaves and targeting sirtuins and their coactivators (NAD + and AMPK)

Sirtuins, guarantors of cell longevity

Scientific investigations conducted to elucidate the mysteries of longevity have revealed mechanisms and markers that can limit the decline of these cellular functions. In particular, this is the case for sirtuins. Their effect on longevity depends on the availability of the coenzyme NAD+, required for the correct mitochondrial functioning and the production of energy, and of AMPK, an energy sensor that protects cellular metabolism.

Thanks to new studies conducted on different models of epidermal and dermal aging, SILAB has demonstrated the transversal action of LONGEVICELL® on sirtuins 1, 3, 6 and 7 and their coactivators (NAD + and AMPK). The active ingredient has thus positive effects on many mechanisms linked to aging, in particular by improving mitochondrial activity and limiting glycation and the onset of cell senescence.

A rapid anti-aging action on the face and body

Due to its favorable impact on these cell mechanisms, LONGEVICELL® limits protein oxidation and boosts the production of energy at the level of the epidermis, while improving the quality of the dermal matrix.

As of 14 days, these effects are shown by remarkable benefits to the face and body: the skin of Caucasian and Asian volunteers is smoothed, and complexion radiance is revived. In addition, after 28 days, the skin gains in elasticity and firmness, and wrinkles are attenuated. These benefits are perceived by Caucasian volunteers themselves: 100% of them find their skin smoother (body) and more luminous (face) and 95% of them consider this care to be an anti-wrinkle product.

A traceable, secure supply of myrtle

SILAB’s development of LONGEVICELL® involved the optimal use of oligogalacturonans present in the leaves of myrtle. With concern for the sustainability of its supply chains, SILAB has selected Moroccan suppliers certified for organic agriculture for its sourcing. A control audit conducted by SILAB on the different steps used to produce the raw material has validated its quality and ensures its traceability back to the harvest site.

LONGEVICELL® is a genuine promoter of longevity and is recommended in all anti- aging face and body care products.

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