Provital introduces two advanced actives to connect the cosmetic world with the medical-aesthetic field.
Driving this innovation forward, Intensilk™ is the first cosmetic active to mimic caloric restriction in adipocytes. Coming from locally sourced apple blossom, Intensilk™ remasters longevity science to dermohack the body for an intensive cellulite treatment with a comprehensive remodeling action on both fat reduction and tissue architecture.
A multi-omic analysis reveals its ability to reprogram adipocyte metabolism from lipid storage to recycling by triggering caloric restriction pathways (PI3K–Akt–mTOR modulation) and activating lipophagy to return energy back to the skin.
Backed by advanced in vitro and in vivo research, Intensilk™ targets all key physiological factors in cellulite development:
- Remodeling tissue architecture by acting simultaneously on lipophagy, adipogenesis, lipolysis, inflammation, while remodeling dermal and hypodermal extracellular matrix.
- Reducing “orange peel” appearance by decreasing lipid accumulation, smoothing dimples, restoring firmness, and achieving even greater efficacy when combined with mechanical massages.
Bridging these benefits, Intensilk™ offers a longevity-driven approach against cellulite appearance for a healthier, more youthful skin texture.
Complementing this innovation, Sculpup™ is Provital’s response to today’s consumers, who are looking for inclusive and non-invasive body cosmetic solutions that are aesthetic surgery-inspired.
An authentic beauty enhancer comes from smart proadipogenic blackberry (patent pending) that broadens the possibilities of body volumisers with new efficacies supported by massive data analysis.
Sculpup™ is a natural active ingredient, 100% of natural origin (ISO 16128) and COSMOS certified, which enhances bust and buttocks volume and firmness.
Our in vitro massive data studies have demonstrated that Sculpup™ significantly modulates the expression of genes related to increased volume—more than 3,500 genes in total. It boosts adipocyte metabolism, acts on collagen and has a high antioxidant capacity, promoting fuller, firmer contours with a lasting effect.
Our in vivo efficacy test on a panel of Caucasian and Brazilian women volunteers demonstrated that it increases bust volume by one extra cup size and buttock circumference by up to 3 cm.
This innovative active enhances authentic beauty with smart, proadipogenic organic blackberry.
Together, these two actives redefine body care by merging scientific precision with aesthetic performance, opening new pathways for high-performance, results-driven solutions.