Novel proteoglycan molecule for 24-hour binding skin hydration

Published: 8-Dec-2025 Featured companies: Evolved By Nature
Ingredients

You deserve better than hyaluronic acid (HA). In fact, you deserve something 4x better

Activated Silk™ Hydrogel delivers 4x the power of mid- and high–molecular weight HA, along with 24-hour clinically proven hydration.

It’s exceptionally effective, yet carries no risk of inflammation or irritation, making it suitable for sensitive skin and for daily use, even around the eyes.

This novel proteoglycan molecule binds directly to skin keratin, allowing it to stay on the skin and maintain long-lasting moisture even after rinsing. That’s what makes it a game-changer for both rinse-away and leave-on products.

Activated Silk™ Hydrogel also binds water to every molecule, enabling powerful hydration at low concentrations. In other words: you can use less Hydrogel to replace more HA, without
compromising performance.

Ready to join the new wave of hydration? Contact us for clinical studies, samples, or a chat, at support@evolvedbynature.com

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Evolved By Nature is a life sciences company that creates high-performing, more sustainable ingredients for skincare, beauty, fashion and beyond
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Goodbye HA. Hello Hydrogels.

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Despite its long-standing presence in skincare, hyaluronic acid (HA) presents a list of challenges for both formulators and consumers. It can irritate sensitive skin and often fails HRIPT testing, making "dermatologist-tested" or "hypoallergenic" claims harder to achieve for brands and its mechanism of action, which pulls water from the environment, can backfire in dry climates by drawing moisture out of the skin instead of into it

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Goodbye HA. Hello Hydrogels.

Despite its long-standing presence in skincare, hyaluronic acid (HA) presents a list of challenges for both formulators and consumers. It can irritate sensitive skin and often fails HRIPT testing, making "dermatologist-tested" or "hypoallergenic" claims harder to achieve for brands and its mechanism of action, which pulls water from the environment, can backfire in dry climates by drawing moisture out of the skin instead of into it
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