Pterostilbene a natural ingredient, a more stable analogue of resveratrol, has been shown to be helpful in the management of several age-related disorders and aging symptoms by modulating age-related physiological mechanisms viz., antioxidant, anti-inflammatory and anti-glycation pathways (1). Preclinical evaluations have shown that the pterostilbene enriched extract has potential antioxidant ability by the virtue of its radicle scavenging activity. The extract effectively scavenged the DPPH (2,2-Diphenyl-1-Picrylhydrazyl) free radical and the activity was comparable to resveratrol and kojic acid. The extract also inhibited the activity the tyrosinase enzyme in vitro and inhibited melanin production and UV induced damage in vivo in the melanocytes (2).
A clinical study evaluated the anti-aging and skin brightening effect of pTeroWhite cream in healthy volunteers. The study was carried out in 38 healthy volunteers by dermatological assessment, non-invasive instrument assessment, and imaging assessment. The cream effectively improved skin brightness, elasticity, reduced the appearance of fine lines, wrinkles, and improved skin texture as compared to baseline. The study concluded that application of pTeroWhite cream twice daily for 8 weeks was safe, and improved skin texture tone, and helped in keeping skin moisturized, supple and young (3).
The company ensures the sustainable supply of the active ingredient through its award-winning 10-year reforestation program in India to cultivate 166,600 kino samplings on 250 acres of forest land.
References
- Li Y-R, Li S, Lin C-C. Effect of resveratrol and pterostilbene on aging and longevity. Biofactors 2018; 44(1):69-82.
- Majeed M et al. A randomized study to determine the sun protection factor of natural pterostilbene from Pterocarpus marsupium. Cosmetics. 2020; 7(1):16.
- Majeed M, Majeed S, Jain R et al. An open-label single-arm, monocentric study assessing the efficacy and safety of natural pterostilbene (Pterocarpus marsupium) for skin brightening and antiaging effects. Clin Cosmet Investig Dermatol. 2020; 13:105-116.
