New OEDTest helps cosmetic manufacturers detect harmful side effects

By Becky Bargh 13-Aug-2018

Swiss-based testing company SGS developed the technology to quantify the activity of estrogenic endocrine disruptors in beauty products

SGS has introduced a new OEDTest to help cosmetic manufacturers detect endocrine chemical distributor (EDC) molecules in cosmetic products.

EDC’s are natural or chemical compounds that have the ability to interfere with the human hormone system and are linked to diabetes, hormone-sensitive cancers in women and men, obesity, and male and female reproduction.

The OEDTest works by screening the sample for endocrine distributor activity. Cellular tests are then used to identify agonist and antagonist effects; these find the disruptor to the hormone receptor creating a signal to disrupt the endocrine system involved with gene transcription.

The results are then evaluated and used by toxicologists when producing a Product Information File.

Until now, manufacturers have relied on laboratory techniques, including HPLC, GC and mass spectrometry, which only focus on molecules recorded in screening libraries.

Said to take a maximum of two weeks to complete, SGS specialists will also offer advice on possible reformulations and potential solutions for eliminating inhibiting molecules.

The OEDTest can be used to test product packaging, including its content interactions, and equipment that comes in contact with skin.

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