In the modern cosmetics industry, microbial safety is not optional, it is a regulatory requirement and a brand differentiator. A preservative challenge test, also known as preservative efficacy testing (PET), ensures that your product can withstand microbial contamination and remain safe, effective, and compliant throughout its lifecycle.
At QACS, we provide specialized challenge testing for cosmetics, grounded in more than 20 years of experience. Our laboratory performs over 50,000 preservative challenge tests per year, helping clients bring microbiologically stable products to market with confidence.
Why preservative efficacy testing matters
Cosmetic products, particularly those with high water content, organic compounds, or reduced preservative systems, are highly susceptible to microbial contamination. Such contamination can compromise product integrity, pose health risks to consumers, and lead to costly recalls, loss of brand reputation, and non-compliance with regulatory requirements. Identifying and mitigating these risks early through microbiological testing is essential for responsible product development and global market readiness.
Preservative efficacy testing simulates contamination under controlled laboratory conditions to evaluate how effectively a formulation resists microbial growth. Testing is essential for compliance with EU Regulation No. 1223/2009 and supports global safety and quality standards.
QACS: a trusted testing partner for cosmetics
With a team of over 170 scientific experts, ISO 17025 accreditation, and GMP-certified facilities, QACS offers unmatched depth and scale in microbiological testing for cosmetics. We successfully test thousands of products annually, and support thousands of cosmetic formulations across more than 50 countries.
Our portfolio includes a wide range of standardized and specialized preservative challenge testing protocols, such as:
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ISO 11930 Challenge Test – The internationally recognized gold standard for preservative efficacy in cosmetics
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USP <51> Preservative Effectiveness Test – Commonly used for personal care products, especially for the U.S. market
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Re-inoculation Challenge Protocol – A dynamic method to assess preservative performance over time through repeated contamination cycles
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Wipe Protocol – Designed specifically for pre-moistened towelettes and similar delivery systems
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Vegan Challenge Protocol – Developed for preservative testing in vegan and “free-from” formulations requiring alternative microbiological approaches
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Synergistic Effect Evaluation – We test preservative and booster combinations to identify enhanced antimicrobial performance. Ideal for mild formulations, this service helps reduce preservative load while ensuring safety and efficacy.
Each protocol is carefully selected or adapted based on your product’s formulation, intended use, and target market. Whether you're testing a serum, cream, lotion, wipe, or cleanser, our team ensures your preservative system meets the highest standards.
Real-time results
QACS is built for both precision and speed. With real-time reporting systems, our clients stay informed throughout the testing process. Whether you're developing a new formulation or updating an existing preservative system, we deliver timely, clear, and regulatory-ready results.
Our expertise extends beyond testing—we help you solve problems, adapt to evolving regulations, and position your products for global market success.
Partner with QACS for your next cosmetic preservative challenge test. With decades of experience, advanced protocols, and scientific excellence, we are the partner of choice for brands who take product safety seriously.
Learn more
info@qacslab.com | +30 210 29 34745
