Sytheon Sytheon

315 Wootton Street
Unit N
NJ 07005
United States

+1 973 988 1075



Sytheon is an innovative research-based company committed to developing high-performance active ingredients for the personal care since 2006. Sytheon’s global headquarters is located in the US with European affiliate in France


Every active ingredient in the Sytheon portfolio is inspired by nature and “Built for Performance.” Moreover, all active ingredients are scientifically and clinically validated to improve the health and beauty of the skin.

In line with our top ingredient Sytenol A (Bakuchiol), Sytheon features ingredients that combat aging and pollution, promote well-aging and hydration and provide solution for problem skin or augment skin’s defenses against UV or blue light.

Key Personnel

Dr. Ratan K Chaudhuri
Founder, President and CEO

Francois Marchio
COO and Managing Director
Sytheon France

Technologies / New Products / Patents

Sytheon develops and offers a wide range of scientifically and clinically validated ingredients for improving the health and beauty of skin.

Sytheon provides innovative solutions in the areas of: ageing skin, skin protection, problem skin, sun protection, pigmentation control, skin hydration, barrier function, photostabilisation and hair fibre protection.

Sytheon has several publications and issued and pending US and European patents.

Asyntra D-Stress CBD-Alt: Amplify the Power of CBD/Hemp Oil De-stress your Skin

Asyntra D-Stress CBD-Alt is a patent pending carefully crafted product that works on its own and in synergy with CBD/Hemp Oil, amplifying its most positive attributes.

Asyntra D-Stress CBD-Alt maintains the levels of Anandamide, the 'bliss molecule', by inhibiting the enzymatic activity of transport enzyme FABP5 and degradation enzyme FAAH thus stimulating the healing effects of Anandamide.

The healing effect of Asyntra D-Stress CBD-Alt lowers the levels of the stress marker 'Cortisol', which fuels inflammation, while concomitantly strengthening skin's barrier function for visibly smoother, hydrated and more radiant looking skin. REACH registered.

VitaSynol C: Stable Lipophilic Vitamin C Ester

Tetrahexyldecyl Ascorbate is a very stable, oil-soluble Vitamin C ester but has no inherent capabilities as an antioxidant because all hydroxyl groups are esterified.

VitaSynol C is truly a precursor of Vitamin C, release of which reduces cell damage triggered by UVB and suppresses UV-induced melanogenesis through ROS scavenging.

Since release of Vitamin C may take hours before it shows protective effect, it is prudent to include an effective antioxidant like Synoxyl AZ or Sytenol A to VitaSynol C formulations. REACH registered. Globally approved.

Synoxyl AZ: Microbiome Friendly 24/7 Prevention & Repair of Photoaging

Acetyl Zingerone (AZ) is a multi-targeted antiaging molecule designed to counteract aging before it happens and to reverse key signs of photo-damaged skin.

AZ prevents skin damage and nurtures skin’s own ability to maintain the integrity of the ECM for optimal health and appearance throughout life. REACH registered. Patented product

Key attributes:

  1. All-in-one antioxidant, quencher and selective chelator. First in the industry
  2. Reduces both immediate and delayed skin damage (↓CPDs) First in the industry
  3. Photochemically stable antioxidant in contrast to many conventional antioxidants
  4. Placebo controlled clinical studies revealed significant improvement in skin defense and reduction in wrinkle, pigmentation and skin redness in photo-aged skin without using sunscreens
  5. Balances skin microbiome diversity and stimulates skin friendly Staph. epidermidis by >20%.

Synastol TC: The Holistic Natural Solution to Pollution & Blue Light Induced Skin Damage with Anti-ageing Benefits

Terminalia Chebula Edible Fruit Extract is a standardised and defined all-natural well ageing ingredient. Clinically proven. TC also provides true “Natural Solution to Pollution and Blue Light Induced skin- Damage”.

Genome-wide expression responses to TC reveals its benefits to skin arise from multiple responses altering tissue architecture, cutaneous circadian rhythm, barrier formation and stimulation of two key hydration biomarkers: Filaggrin and Aquaporin 9. ECOCERT COSMOS Natural. Globally approved

Additional key attributes:

  1. Provides broad-action well aging benefits including reversal of protein glycation
  2. Provides long-lasting skin protection due to cascading antioxidant property
  3. Scavenges reactive oxygen species (ROS) ) and reduces formation of lipid peroxides caused by sun, pollution and blue light
  4. Reduces pollution induced pro-inflammatory biomarkers IL-6 and IL-8.

Sytenol A: The True Natural Alternative to Retinol

Yes, Retinol found its match. That is Sytenol A (Bakuchiol). It has all the major benefits of retinol but none of the problems. Bakuchiol was shown in a recent study published in British J Dermatology (180:289-296, 2019; 180:253-254, 2019) to match the established benefits of retinol.

UC-Davis dermatologists concluded that Bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol.

It is all natural, well-defined compound with >99% purity, stable, easy to formulate with, requires no dark room for formulation, can be used during the day and has been shown to stabilise retinol. Natrue certified. REACH registered. Patented product.

Synovea HR & Asyntra SL – The Gold Standards in Skin Brightening & Even Toning

Hexylresorcinol is the New Gold Standard in lightening/even-toning products. Clinically proven to be two to four-times more effective than Hydroquinone.

Also, much superior to kojic acid, licorice, ascorbic acid and its derivatives. Multiple clinical studies with Synovea HR demonstrated its strong performance in skin brightening and hyper-pigmentation control for all skin colour. REACH registered. Patented product. Globally approved.

Asyntra SL is a liquid synergistic version of HR composed of Caprylic/Capric triglycerides (and) Hexylresorcinol (and) Ethyl Linoleate. REACH registered. Globally approved.

HydraSynol DOI: A Smart Lipophilic Skin Hydrator & Barrier Builder

Isosorbide Dicaprylate is a smart skin hydrator and barrier builder that intelligently provides optimum hydration based on skin moisture content/deficit.

Clinically shown to be very effective in providing long-lasting (>48 hrs.) and controlled skin hydration. Works by stimulating Aquaporin-3, Tight Junction, Desmosomes and Epidermal Differentiating genes/proteins. E-Cadherin up-regulation provides broad-action skin homeostasis. ECOCERT COSMOS Natural. REACH registered. Patented Product.

Synoxyl HSS: A Solution to Make Hawaii-Compliant Sunscreen

Trimethoxybenzylidene Pentanedione is a breakthrough patented product. Synoxyl HSS is an excellent photostabilizer, provides in-vivo SPF boosting by 50% for both organic and inorganic sunscreens and protects skin by inhibiting up-stream ROS cascade.

Perfect product for developing Octocrylene and Oxybenzone-free broad-spectrum sunscreens. REACH registered. Patented product.

Synactin AC: Designed to Alleviate all Five Key Acne Targets

Caprylic/Capric triglycerides (and) Ethyl Linoleate (and) Hexylresorcinol is clinically proven to mitigate acne-affected skin. Synactin AC designed to alleviate all five key acne targets:

  1. Hyper-keratinisation
  2. Bacterial population
  3. Sebum control
  4. Inflammation
  5. Pigmentation.

REACH registered. Globally approved.

Synovea EL: A Smart Synergist with Multiple Skin Benefits

EL is a neutral, lipid-soluble form of Linoleic acid (LA) which is an essential fatty acid needed for skin nourishment. Multiple skin benefits:

  1. Maintains stratum corneum acidity
  2. Maintains barrier function
  3. Decreases sebaceous gland activity
  4. Regulates follicular keratinisation
  5. Inhibits post-inflammatory hyperpigmentation
  6. Reduces skin pigmentation.

ECOCERT COSMOS Natural. REACH registered. Globally approved.

Major Markets

Personal & skin care and selective hair care markets

Specialised Services

Develops exclusive customer specific projects in the areas of synthetic and natural compounds, and deliver cost–effective solutions to satisfy customer needs. Provides turn-key solutions to customers for bringing effective products to the market.

Global Capabilities

Sytheon products are marketed all over the world either direct or through country/region specific distributors.


Synovea; Asyntra; Synastol; HydraSynol; Sytenol; Synactin; Synoxyl; VitaSynol;